- Con 20 goles:

Landon Donovan (LA Galaxy)

- Con 18 goles:

Kenny Cooper (FC Dallas)

- Con 16 goles:

Juan Pablo Angel (New York Red Bulls)

- Con 15 goles:

Edson Buddle (LA Galaxy)

- Con 13 goles:

Brian Ching (Houston Dynamo)

- Con 11 goles:

Conor Casey (Colorado Rapids)
Luciano Emilio (DC United)

- Con 10 goles:

Jaime Moreno (DC United)

- Con 9 goles:

Chris Rolfe (Chicago Fire)
Alejandro Moreno (Columbus Crew)
Chad Barrett (Toronto FC)

- Con 8 goles:

Taylor Twellman (New England Revolution)
Jeff Cunningham (Toronto FC/FC Dallas)
Steve Ralston (New England Revolution)

- Con 7 goles:

Davy Arnaud (Kansas City Wizards)
Dwayne De Rosario (Houston Dynamo)
Yura Movsisyan (Real Salt Lake)
Cuauhtémoc Blanco (Chicago Fire)
Dave Van den Berg (New York Red Bulls)
Guillermo Barros Schelotto (Columbus Crew)

- Con 6 goles:

Robbie Findley (Real Salt Lake)
Jimmy Conrad (Kansas City Wizards)
Javier Morales (Real Salt Lake)
Darren Huckerby (San Jose Earthquakes)
Omar Cummings (Colorado Rapids)
Arturo Alvarez (FC Dallas/San Jose Earthquakes)
Adam Cristman (New England Revolution)

- Con 5 goles:

Brad Evans (Columbus Crew)
Claudio López (Kansas City Wizards)
Colin Clark (Colorado Rapids)
Scott Sealy (San Jose Earthquakes)
Alecko Eskandarian (Chivas USA)
Tom McManus (Colorado Rapids)
Ryan Johnson (San Jose Earthquakes)
Mike Magee (New York Red Bulls)
Alan Gordon (LA Galaxy)
Santino Quaranta (DC United)
Ante Razov (Chivas USA)
Dominic Oduro (FC Dallas)
Fabián Espíndola (Real Salt Lake)
John Thorrington (Chicago Fire)
David Beckham (LA Galaxy)
Sacha Kljestan (Chivas USA)
Danny Dichio (Toronto FC)
Robbie Rogers (Columbus Crew)

- Con 4 goles:

Jeff Larentowicz (New England Revolution)
Amado Guevara (Toronto FC)
Steven Lenhart (Columbus Crew)
Rohan Ricketts (Toronto FC)
Brian McBride (Chicago Fire)
Justin Braun (Chivas USA)
Chad Marshall (Columbus Crew)
Ronnie O'Brien (San Jose Earthquakes)
Nate Jaqua (Houston Dynamo)
Kei Kamara (Houston Dynamo)
Marcelo Gallardo (DC United)
Kheli Dube (Columbus Crew)
Jesse Marsch (Chivas USA)

- Con 3 goles:

Herculez Gómez (Kansas City Wizards)
Stuart Holden (Houston Dynamo)
Eddie Gaven (Columbus Crew)
Sasha Victorine (Kansas City Wizards)
Dane Richards (New York Red Bulls)
Kenny Mansally (New England Revolution)
Josh Wolff (Kansas City Wizards)
Andre Rocha (FC Dallas)
Jack Jewsbury (Kansas City Wizards)
Brad Davis (Houston Dynamo)
Jason Garey (Columbus Crew)
Brian Mullan (Houston Dynamo)
Atiba Harris (Chivas USA)
Abe Thompson (FC Dallas)
Christian Gómez (Colorado Rapids)
Jorge Flores (Chivas USA)
Jozy Altidore (New York Red Bulls)
Kyle Beckerman (Real Salt Lake)

- Con 2 goles:

Drew Moore (FC Dallas)
Shea Salinas (San Jose Earthquakes)
Shea Salinas (San Jose Earthquakes)
Francis Doe (DC United)
Jonathan Bornstein (Chivas USA)
Justin Mapp (Chicago Fire)
Marco Velez (Toronto FC)
Marvell Wynne (Toronto FC)
Jamison Olave (Real Salt Lake)
Abdus Ibrahim (Kansas City Wizards)
Michael Harrington (Chicago Fire)
Ricardo Clark (Houston Dynamo)
Mike Petke (Colorado Rapids)
Khano Smith (New England Revolution)
Stephen King (Chicago Fire)
Paulo Nagamura (Chivas USA)
Gonzalo Segares (Chicago Fire)
Carey Talley (Chivas USA)
Nick LaBrocca (Columbus Crew)
Maurice Edu (Toronto FC)
Kevin Goldthwaite (New York Red Bulls)
Brad Evan (Columbus Crew)
Clyde Simms (DC United)
John Cunliffe (San Jose Earthquakes)
Ramiro Corrales (San Jose Earthquakes)
Danleigh Borman (New York Red Bulls)
Kenny Deuchar (Real Salt Lake)
Adam Moffat (Columbus Crew)
Tomasz Frankowski (Chicago Fire)
Sainey Nyassi (New England Revolution)